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Jocelyn Rylee
Mar 3
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Is Medicine Captured?

By Dr. Nick Norowitz, MD, PhD

I recently caught a line in a paper that stopped me in my tracks.

The paper was published in a major journal, The Lancet Diabetes & Endocrinology, and had been used by legacy and social media to proclaim the benefits of a new generation weight-loss drug: Retatrutide.

Think Ozempic on steroids.

Retatrutide is a newer generation GLP-1 receptor agonist that targets two other pathways, which is why it’s sometimes called a “GLP-3.”

But that is not the point.

If you go to page 678 in the PDF, there’s a line:

“The study sponsor provided the study drugs and was involved in the study design, data collection, data analysis, data interpretation, and writing of the report.”

In this case, the study sponsor was Eli Lilly, the pharma company that stands to profit from the drug they’ve patented.

Now, it’s completely understandable in a capitalistic society that pharma companies are going to fund drug trials. That’s obvious, and it’s not something with which I take issue per se. That’s capitalism, and it drives innovation.

But those five words at the end — “and writing of the report” — stopped me.

They are explicit: that pharma company helped write the published paper that went through peer review, got the stamp of academia, and will ultimately push the needle on the standard of care.

The reason I take issue here — the reason this is so insidious — is because when this line is crossed, when the pharma company isn’t just funding and designing trials but also helping with data analysis and writing the report, the framing ends up being such that seeds of misinformation are planted.

Let’s take a look at the interpretation presented in the abstract, which is primarily what gets read.

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